Anyone who has any non-gis enterpise databases that have some sort of relationship to the GIS data will almost certainly be using personal geodabases. Yes you may use file geodabases to do the gis manipulation - it is a lot quicker - but you then move the data to a personal geodatabase, fire up MS Access do all the cool things in there and then move it back to the file geodabase if needed. I have a fair number of pythons scripts that do things like this. One in particular copies data from a SDE geodatabase into a pgdb then runs a MS Access macro that uses just under 80 queries to modify the data by joining to a number of corporate databases before moving to a file geodatabase. To me, this is the sort of workflows and functionality we lose with no personal geodatabase support.
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