I have an intermittent error, which other colleagues have experienced as well, where having created working python toolboxes ArcCatalog 10.1 will crash on opening with a serious application error. I then delete the Normal.gxt file, which restores ArcCatalog but I cannot see the python toolboxes. Oddly eventually they do reappear, usually after a few uses of arcmap, and will function again. I find the crash is far more likely to happen if I am testing toolboxes but this is not always the case.
Furthermore I do not get this issue if I use the python toolboxes in ArcMap, they are always present and always work.
Has anyone experienced this issue and if so know how to resolve it?