Hot Spot error

[KayYamakawa]

I got hotspot updateParameters Syntax Error in ArcGIS 10.4 .  I run it before, No error.   After I had to install Aptana_Studio_3_Setup_3.6.1 , Node.js and  Git. I started to get  that error .  I was following UpdateParameters Syntax Error on all Spatial Stats tools , but not fixing.  Please give me guidance! 

*************************************  Error *******************************************

ERROR
updateParameters Syntax Error: Runtime error Traceback (most recent call last): File "c:\program files (x86)\arcgis\dk10.4\desktop10.4\ArcToolbox\Toolboxes\Spatial Statistics Tools.tbx#HotSpots_stats.UpdateParameters.py", line 6, in File "C:\Program Files (x86)\ArcGIS\DK10.4\Desktop10.4\ArcToolBox\Scripts\WeightsUtilities.py", line 20, in import SSUtilities as UTILS File "C:\Program Files (x86)\ArcGIS\DK10.4\Desktop10.4\ArcToolBox\Scripts\SSUtilities.py", line 29, in import matplotlib.path as PATH File "C:\Python27\Dk104\ArcGIS10.4\lib\site-packages\matplotlib\__init__.py", line 169, in from urllib2 import urlopen File "C:\Users\Yxxxxx\AppData\Local\Continuum\Anaconda2\Lib\urllib2.py", line 94, in import httplib File "C:\Users\Yxxxx\AppData\Local\Continuum\Anaconda2\Lib\httplib.py", line 72, in import socket File "C:\Users\Yxxxxx\AppData\Local\Continuum\Anaconda2\Lib\socket.py", line 47, in import _socket ImportError: DLL load failed: %1 is not a valid Win32 application.

[DanPatterson_Retired]

That patch is several years old.  I suspect it may have corrupted your installation.  I would uninstall or go back to a previous restore point in windows

[KayYamakawa]

I did:  uninstalled ArcGIS 10.4 ,Aptana_Studio_3_Setup_3.6.1 , Node.js and  Git and installed ArcGIS 10.4 only, but still error I got.  ???

[KayYamakawa · Accepted solution]

I added C:\Program Files (x86)\ArcGIS\Desktop10.4\ArcToolBox\Scripts to PYTHONPATH, even I saw Desktop10.4.pth has it.  Then No error !  Thank you.