I did a search using... Chrome AGOL ... on this site with mixed review. There is even a poll suggesting that about half use Chrome as their preferred browser. You may have to elaborate where you are accessing AGOL... work, home? If work, what are the security setting/access restrictions? Are you getting error messages? can you access AGOL from the opposite location (ie home/work) without issue.
Anything to narrow it down, or you are going to get a litany of "me too" or "not me" responses