I haven't Dan Patterson but I will in the morning. Just for fun I created a scratch fgdb, with a scratch feature class with a couple fields in it. First I just assigned a default value to each of the fields; I was able to save the fields view and added a couple of points. All good. I then changed the default values again, saved and added a couple more points. All good.
Then created a domain with a few values, and set default values based on the domain; added a cople points and that worked just fine. I also went in and changed the default domain value. All good, all around.
The project, database, and domains are all part of the Address Data Mangagement Solution. I've experienced a few gremlin like problems besides this one. I'm not sure if it's my ArcGIS Pro installation, my laptop, or the aprx itself.
I'll post up tomorrow what I come up with using the tool.
Chris Fox
That should just about do it....