I have also noticed this issue as of 2.6/2.7. I went through the same process of uninstalling the program and reinstalling, updating the GPU driver, adjusting Display/Rendering options, and even increased my system's pagefile.sys size. Regardless of these changes, I continue to notice issues.
Description of Issues:
In an active ArcGIS Pro Project File, manual processes (checking unchecking layers, opening Catalog Pane, expanding a geodatabase dropdown list, clicking different objects in a layout) that used to take fractions of seconds to toggle, not throw ArcGIS Pro into a 2-5 minutes pause before a refresh occurs. For more complicated analytical processes (using tools, georeferencing, accessing WMS server data, etc.) that used to take 30 seconds to a minute, now cause my map or layout view to go black for 2-5 minutes before a refresh occurs.